公的補助金等
奈良中央信用金庫 第16回ちゅうしん地域中小企業振興助成金制度
経済産業省 ものづくり・商業・サービス新展開支援補助金 (15次公募)
国際協力機構(JICA)2018年度第一回中小企業海外展開支援事業
経済産業省 中小企業等経営強化法に関わる経営力向上計画の認定
経済産業省 平成27年度補正ものづくり・商業・サービス新展開支援補助金
奈良中央信用金庫 第16回ちゅうしん地域中小企業振興助成金制度
経済産業省 ものづくり・商業・サービス新展開支援補助金 (15次公募)
経済産業省 平成27年度補正ものづくり・商業・サービス新展開支援補助金
経済産業省 中小企業等経営強化法に関わる経営力向上計画の認定
国際協力機構(JICA)2018年度第一回中小企業海外展開支援事業
知的財産
特願2023-017378 間葉系幹細胞の培養方法
特願2022-127097 細胞の投与液
特許第7847359号 NK細胞の培養方法
特許第7769362号 脂肪組織由来間葉系幹細胞の培養方法
特開2012-205581 MHC非拘束性細胞傷害性細胞の製造方法
登録商標
登録番号6497397 GRANDSOUL AGENT®
論文
Natural killer cell-based senotherapy: a promising strategy
for healthy aging.
Nakazawa T, Yamanishi R, Morimoto T, Matsuda R. Frontiers in
Immunology. 16. 2025
Immunotherapy using allogenic NK cells downregulates
mitochondrial-related genes and inhibits the OXPHOS system of
malignant meningioma.
Maeoka R, Matsuda R, Nakazawa T, Mochida Y, Ouji-Sageshima N,
Yamada K, Morimoto T, Takeshima Y, Yamada S, Nishimura F, Park
YS, Ito T, Nakagawa I. Biomed Pharmacother. 187, 11809. 2025
Characterization of HIF-1α Knockout Primary Human Natural
Killer Cells including Populations in Allogeneic
Glioblastoma.
Nakazawa T, Morimoto T, Maeoka R, Yamada K, Matsuda R, Nakamura
M, Nishimura F, Yamada S, Park YS, Tsujimura T, Nakagawa I.
Int.
J. Mol. Sci. 25(11), 5896 2024
Bulk RNA sequencing reveals the comprehensive genetic
characteristics of human cord blood-derived natural killer
cells.
Morimoto T, Nakazawa T, Matsuda R, Maeoka R, Nishimura F,
Nakamura M, Yamada S, Nakagawa I, Park YS, Tsujimura T
Regen Ther. 25:367-376. 2024
Antitumor effects of intravenous natural killer cell infusion
in an orthotopic glioblastoma xenograft murine model and gene
expression profile analysis.
Morimoto T, Nakazawa T, Matsuda R, Maeoka R, Nishimura F,
Nakamura M, Yamada S, Tsujimura T, Park YS, Nakagawa I
Int J Mol Sci. 25(4), 2435 2024
Therapeutic anti-KIR antibody of 1-7F9 attenuates the
anti-tumor effects of expanded and activated human primary
natural killer cells on in vitro glioblastoma-like cells and
orthotopic tumors derived therefrom.
Maeoka R, Nakazawa T, Matsuda R, Morimoto T, Shida Y, Nakamura
M, Nishimura F, Yamada S, Nakagawa I, Park YS, Tsujimura T,
Nakase H.
Int J Mol Sci. 24(18), 14183 2023
Local administration of shikonin improved the overall
survival in orthotopic murine glioblastoma models with
temozolomide resistance.
Maeoka R, Ouji Y, Nakazawa T, Matsuda R, Morimoto T, Yokoyama S,
Yamada S, Nishimura F, Nakagawa I, Park YS, Yoshikawa M, Nakase
H.
Biomed Pharmacother. 166; 115296 2023
CIS deletion by CRISPR/Cas9 enhances human primary natural
killer cell functions against allogeneic glioblastoma.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nakamura M,
Nishimura F, Ouji N, Yamada S, Nakagawa I, Park YS, Ito T,
Nakase H, Tsujimura T.
J Exp Clin Cancer Res. 42, 205. 2023
An Efficient Feeder-free and Chemically-defined Expansion Strategy for Highly Purified Natural Killer Cells Derived from Human Cord Blood. Nakazawa T, Maeoka R, Morimoto T, Matsuda R, Nakamura M, Nishimura F, Yamada S, Nakagawa I, Park YS, Ito T, Nakase H, Tsujimura T. Regen Ther. 24: 32-42. 2023
Does ghrelin regulate intestinal motility in rabbits? An in
vitro study using isolated duodenal strips.
Zhang S, Kaiya H, Kitazawa T.
Gen Comp Endocrinol. 16;344:114384 2023
Evolution of Vertebrate Hormones and Their Receptors:
Insights from Non-Osteichthyan Genomes.
Kuraku S, Kaiya H, Tanaka T, Hyodo S.
Annu Rev Anim Biosci. 15;11:163-182 2023
Ghrelin, not corticosterone, is associated with transitioning
of phenotypic states in a migratory Galliform.
Marasco V, Kaiya H, Pola G, Fusani L.
Front Endocrinol (Lausanne). 9;13:1058298 2023
Natural Killer Cell-based Immunotherapy Against
Glioblastoma.
Morimoto T, Nakazawa T, Maeoka R, Nakagawa I, Tsujimura T,
Matsuda R.
Int J Mol Sci. 24 (3), 2111 2023
Capability of Human Dendritic Cells Pulsed with Autologous
Induced Pluripotent Stem Cell Lysate to Induce Cytotoxic T
Lymphocytes Against HLA-A33-matched Cancer Cells.
Nakazawa T, Maeoka R, Morimoto T, Matsuda R, Nakamura M,
Nishimura F, Yamada S, Nakagawa I, Park YS, Nakase H, Tsujimura
T.
Int J Mol Sci. 23(21), 12992 2022
Establishment of an efficient ex vivo expansion strategy for
human natural killer cells stimulated by defined cytokine
cocktail and antibodies against natural killer cell-activating
receptors.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nakamura M,
Nishimura F, Yamada S, Nakagawa I, Park YS, Nakase H, Tsujimura
T.
Regen Ther. 21:185-191. 2022
Evaluation of comprehensive gene expression and NK
cell-mediated killing in Glioblastoma cell line-derived
spheroids.
Morimoto T, Nakazawa T, Matsuda R, Nishimura F, Nakamura M,
Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase H.
Cancers. 13(19), 4896 2021
Ex vivo Expanded and Activated Natural Killer Cells Prolong
the Overall Survival of Mice with Glioblastoma-like
Cell-Derived Tumors.
Shida Y, Nakazawa T, Matsuda R, Morimoto T, Nishimura F,
Nakamura M, Maeoka R, Yamada S, Nakagawa I, Park YS, Yasukawa M,
Tojo T, Tsujimura T, Nakase H.
Int J Mol Sci. 22(18), 9975 2021
CRISPR–Cas9–mediated TIM3 knockout in human Natural Killer
Cells Enhances Growth Inhibitory Effects on Human Glioma
Cells.
Morimoto T, Nakazawa T, Matsuda R, Nishimura F, Nakamura M,
Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase H.
Int J Mol Sci. 22(7), 3489 2021
Isolation of adipose tissue-derived stem cells by direct
membrane migration and expansion for clinical application.
Matsuo Y, Morita H, Yamagishi H, Nakamura M, Takeshima Y,
Nakagawa I, Imanishi J, Tsujimura T.
Hum Cell 2021 34(3):819-824 2021
KHYG-1 Cells With EGFRvIII-specific CAR Induced a
Pseudoprogression-like Feature in Subcutaneous Tumours Derived
from Glioblastoma-like Cells.
Nakazawa T, Murakami T, Natsume A, Nishimura F, Morimoto T,
Matsuda R, Nakamura M, Yamada S, Nakagawa I, Motoyama Y, Park
YS, Tsujimura T, Wakabayashi T, Nakase H.
Anticancer Res. 40:3231-3237. 2020
Effect of CRISPR/Cas9-Mediated PD-1-disrupted primary human
third-generation CAR-T cells targeting EGFRvIII on in vitro
human glioblastoma cell growth.
Nakazawa T, Natsume A, Nishimura F, Morimoto T, Matsuda R,
Nakamura M, Yamada S, Nakagawa I, Motoyama Y, Park YS, Tsujimura
T, Wakabayashi T, Nakase H.
Cells. 9(4), 998 2020
Ex vivo-expanded highly purified natural killer cells in
combination with temozolomide induce antitumor effects in
human glioblastoma cells in vitro.
Tanaka Y, Nakazawa T, Nakamura M, Nishimura F, Matsuda R, Omoto
K, Shida Y, Murakami T, Nakagawa I, Motoyama Y, Morita H,
Tsujimura T, Nakase H.
PLOS ONE. 26;14(3):e0212455 2019
Expression of peptide transporter 1 has a positive
correlation in protoporphyrin IX accumulation induced by
5-aminolevulinic acid with photodynamic detection of non-small
cell lung cancer and metastatic brain tumor specimens
originating from non-small cell lung cancer.
Omoto K, Matsuda R, Nakazawa T, Nishimura F, Nakagawa I,
Motoyama Y, Nakamura M, Nakase H et al.
Photodiagnosis Photodyn Ther. 25:309–316. 2019
Novel Human NK Cell Line Carrying CAR Targeting EGFRvIII
Induces Antitumor Effects in Glioblastoma Cells.
Murakami T, Nakazawa T, Natsume A, Nishimura F, Nakamura M,
Matsuda R, Omoto K, Tanaka Y, Shida Y, Park YS, Motoyama Y,
Nakagawa I, Yamada S, Tamura K, Takeshima Y, Takamura Y,
Wakabayashi T, Nakase H.
Anticancer Res. 38:5049-5056. 2018
Minodronic Acid in Combination with γδT Cells Induces
Apoptosis of Non-small Cell Lung Carcinoma Cell Lines.
Yasukawa M, Nakazawa T, Kawaguchi T, Kawai N, Tsujimura T, Tojo
T, Taniguchi S.
Anticancer Res. 36:5883-5886. 2016
Antitumor effects of minodronate, a third-generation
nitrogen-containing bisphosphonate, in synergy with γδT cells
in human glioblastoma in vitro and in vivo.
Nakazawa T, Nakamura M, Matsuda R, Nishimura F, Park YS,
Motoyama Y, Hironaka Y, Nakagawa I, Yokota H, Yamada S, Tamura
K, Takeshima Y, Omoto K, Tanaka Y, Ouji Y, Yoshikawa M,
Tsujimura T, Nakase H.
J Neurooncol. 129:231-241. 2016
Cytotoxic human peripheral blood-derived γδT cells kill
glioblastoma cell lines: implications for cell-based
immunotherapy for patients with glioblastoma.
Nakazawa T, Nakamura M, Park YS, Motoyama Y, Hironaka Y,
Nishimura F, Nakagawa I, Yamada S, Matsuda R, Tamura K, Sugimoto
T, Takeshima Y, Marutani A, Tsujimura T, Ouji N, Ouji Y,
Yoshikawa M, Nakase H.
J Neurooncol. 116:31-39. 2014
Characterization and expansion of human peripheral blood γδ T
cells.
Tsujimura T, Nakazawa T, Matsuo Y, Imanishi J.
J Kyoto Pref Univ of Med. 118:711-722. 2009
Correlations of sleep disturbance with the immune system in
type 2 diabetes mellitus.
Tsujimura T, Matsuo Y, Keyaki T, Sakurada K, Imanishi J.
Diabetes Res Clin Pract. 85:286-292. 2009
Divergent cytotoxic effects of PKC412 in combination with
conventional antileukemic agents in FLT3 mutation-positive
versus -negative leukemia cell lines.
Furukawa Y, Vu HA, Akutsu M, Odgerel T, Izumi T, Tsunoda S,
Matsuo Y, Kirito K, Sato Y, Mano H, Kano Y.
Leukemia. 21:1005-1014.2007
Involvement of IL-10 and Bcl-2 in resistance against an
asbestos-induced apoptosis of T cells.
Miura Y, Nishimura Y, Katsuyama H, Maeda M, Hayashi H, Dong M,
Hyodoh F, Tomita M, Matsuo Y, Uesaka A, Kuribayashi K, Nakano T,
Kishimoto T, Otsuki T.
Apoptosis. 11:1825-1835. 2006
Inhibitory effects of anti-oxidants on apoptosis of a human
polyclonal T-cell line, MT-2, induced by an asbestos,
chrysotile-A.
Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T,
Hatada S, Katsuyama H, Matsuo Y, Otsuki T.
Scand J Immunol. 61:442-448. 2005
発表
国際学会
CISH knockout by CRISPR/Cas9 enhances human peripheral
blood-derived NK cell functions against allogeneic
glioblastoma.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nishimura F,
Tsujimura T, Nakagawa I.
Annual Meeting of International Society of Cell and Gene Therapy
(ISCT) 2024, Vancouver, Canada
Characterization of CISH-knockout NK cells derived from human
peripheral blood and evaluated the antitumor effects in
allogeneic glioblastoma.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nishimura F,
Tsujimura T, Nakagawa I.
Annual Meeting of American Association of Immunology (AAI)
"IMMUNOLOGY2024", Chicago, USA
Ablation of the intracellular immune checkpoint molecule CIS
potentiates antitumor effects against glioblastoma by unleashing
the functions of NK cells derived from human peripheral
blood.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nishimura F,
Nakamura M, Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase
H.
The 51st Annual Meeting of the Japanese Society for Immunology,
2022, Kumamoto
CRISPR–Cas9–mediated TIM3 knockout in human Natural Killer
Cells Enhances Growth Inhibitory Effects on Human Glioma
Cells.
Morimoto T, Nakazawa T, Matsuda R, Nishimura F, Nakamura M,
Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase H. Annual
Meeting of American Association of Immunology ”IMMUNOLOGY2021",
Virtual meeting
J Immunol May 1, 2021, 206 (1 Supplement) 68.17
Induction of EGFRvIII-targeting CAR-expressing Natural Killer
Cells Derived From Human Induced Pluripotent Stem Cells.
Nakazawa T, Natsume A, Nishimura F, Morimoto T, Matsuda R,
Nakamura M, Nakagawa I, Park YS, Tsujimura T, Wakabayashi T,
Nakase H.
Keystone symposia Emerging Cell Therapies: Realizing the Vision
of NextGen Cell Therapeutics, 2021, Keystone Virtual meeting
Characterization of a novel type NK cell line KHYG-1 carrying
EGFRvIII-specific CAR in glioblastoma cells.
Morimoto T, Nakazawa T, Natsume A, Nishimura F, Matsuda R,
Murakami T, Nakamura M, Nakagawa I, Motoyama Y, Park YS,
Tsujimura T, Wakabayashi T, Nakase H.
Annual Meeting of American Association of Immunology,
”IMMUNOLOGY2020", Hawaii, USA
J. Immunol 2020. 204 (1 Supplement) 170.22
Effect of CRISPR/Cas9-mediated PD-1-disrupted primary human
third-generation CAR-T cells targeting EGFRvIII on human
glioblastoma cell growth.
Nakazawa T, Morimoto T, Natsume A, Nishimura F, Matsuda R,
Murakami T, Nakamura M, Nakagawa I, Motoyama Y, Park YS,
Tsujimura T, Wakabayashi T, Nakase H.
Annual Meeting of American Association of Immunology
”IMMUNOLOGY2020", Hawaii, USA
J. Immunol 2020. 204 (1 Supplement) 170.1
Establishment of an efficient ex-vivo expansion method for
highly purified human natural killer cells and evaluation of
their antitumor activity on glioblastoma.
Nakazawa T, Tanaka Y, Shida Y, Nakamura M, Nishimura F, Matsuda
R, Murakami T, Nakagawa I, Motoyama Y, Tsujimura T, Nakase H.
Keystone Symposia: Innate and Non-Classical Immune Cells in
Cancer Immunotherapy, 2019, Keystone, USA
Capability of dendritic cells loaded with induced-pluripotent
stem cells to induce cancer-responsive T cells from a donor
with HLA class I-A33 alleles in vitro.
Nakazawa T, Nishimura F, Matsuda R, Yamashita Y, Nakamura M,
Nakagawa I, Motoyama Y, Tsujimura T, Nakase H.
European Association for Cancer Research: Defence is the Best
Attack: Immuno-Oncology Breakthroughs, 2019, Barcelona, Spain
Antitumor effects of minodronate, a third-generation
nitrogen-containing bisphosphonate, in synergy with γδT cells in
human glioblastoma in vitro and in vivo.
Nakazawa T, Nakamura M, Matsuda R, Nishimura F, Tsujimura T,
Nakase H et al.
American Association for Cancer Research: Immunobiology of
Primary and Metastatic CNS Cancer: Multidisciplinary Science to
Advance Cancer Immunotherapy Special Conference, 2018, San
Diego, USA
Minodronate exerts antitumor effects against human glioblastoma
in cooperation with peripheral blood-derived γδ T cells.
Nakazawa T, Nakamura M, Matsuda R, Park YS, Motoyama Y, Hironaka
Y, Nishimura F, Nakagawa I, Tamura K, Takeshima Y, Marutani A,
Omoto K, Tanaka Y, Ouji Y, Yoshikawa M, Tsujimura T, Nakase
H.
International Conference of Cancer Immunotherapy and
Macrophages, 2015, Tokyo
Cytotoxic human peripheral blood-derived γδT cells kill
glioblastoma cell lines.
Nakazawa T, Tsujimura T.
The 73rd Annual Meeting of the Japanese Cancer Association,
2014, Yokohama
The effectiveness of valproic acid for malignant glioma in the
temozolomide era.
Matsuda R, Nakamura M, Nakazawa T, Tamura K, Yamada S, Nishimura
F, Nakagawa I, Motoyama Y, Park YS, Nakase H.
The 10th Meeting of the Asian Society for Neuro-Oncology, 2013,
Mumbai
Expansion of human natural killer cells in vitro.
Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 68th Annual Meeting of the Japanese Cancer Association,
2009, Yokohama
Characterization of expanded γδ T cells derived from human
peripheral blood.
Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 67th Annual Meeting of the Japanese Cancer Association,
2008, Nagoya
Determination of heterogeneity of in vitro expanded peripheral
blood γδT cells derived from human peripheral blood.
Shiomi R, Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 38th Annual Meeting of the Japanese Society for Immunology,
2008, Kyoto
Establishment of regulatory γδT cell line derived from human T
cell leukemia virus type I career.
Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 66th Annual Meeting of the Japanese Cancer Association,
2007, Yokohama
Establishment and characterization of regulatory T cell-like γδT
cell line derived from human peripheral blood.
Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 37th Annual Meeting of the Japanese Society for Immunology,
2007, Tokyo
Expansion of NKT cells and specific cytotoxicity against cell
lines derived from multiple myelomas.
Nakazawa T, Tsujimura T, Imanishi J, Matsuo Y.
The 65th Annual Meeting of the Japanese Cancer Association,
2006, Yokohama
Characterization of HIF-1α Knockout Primary Human Natural Killer
Cells in Allogeneic Glioblastoma
Nakazawa T, Yamada K, Hayami H, Morimoto T, Matsuda R, Nishimura
F, Tsujimura T, Nakagawa I.
Annual Meeting of American Association of Immunology (AAI)
"IMMUNOLOGY2025", Hawaii, USA
国内学会
Characterization of HIF-1α knockout primary human natural killer
cells in allogeneic glioblastoma
中澤 務、山田 研吾、速水 宏達、森本 尭之、松田 良介、西村
文彦、辻村 貴弘、中川 一郎
第24回日本再生医療学会総会、2025年、横浜
Efficient feeder-free expansion system for highly purified NK
cells derived from human cord blood
中澤 務、森本 尭之、前岡 良輔、松田 良介、西村 文彦、中村
光利、山田 修一、中川 一郎、辻村 貴弘
第23回日本再生医療学会、2024年、新潟
Functional analysis of inhibitory receptors in natural killer
cell-based immunotherapy against Glioblastoma.
松田 良介、中澤 務、前岡 良輔、森本 尭之、西村 文彦、中村
光利、辻村 貴弘、中川 一郎
第28回日本がん免疫学会総会、2024年、東京
膠芽腫モデルに対する NK 細胞の抗腫瘍効果の検証と抗 KIR2DL1
抗体の影響
前岡良輔、中澤務、森本尭之、松田良介、西村文彦、中村光利、山田修一、中川一郎、辻村貴弘、中瀬裕之
第41回日本脳腫瘍学会学術集会、2023年、新潟
膠芽腫に対するNK細胞療法の研究開発 - オールドルーキーの帰還
-
前岡良輔、中澤務、松田良介、中村光利、山田修一、辻村貴弘、中川一郎
日本脳神経外科学会第82回学術総会、横浜
CISノックアウトヒト同種NK細胞の膠芽腫に対する抗腫瘍効果
中澤務、前岡良輔、森本尭之、松田良介、中村光利、辻村貴弘
第29回日本遺伝子細胞治療学会学術集会、2023年、大阪
Evaluation of Comprehensive Gene Expression and NK Cell-Mediated
Killing in Glioblastoma Cell Line-Derive spheroids.
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
第27回日本がん免疫学会総会、2023年、三重
Targeting a checkpoint molecule enhances human NK cell functions
against allogeneic glioblastoma.
中澤務、前岡良輔、森本尭之、松田良介、中村光利、西村文彦、山田修一、中川一郎、辻村貴弘
日本ゲノム編集学会 第8回大会 、2023年、東京
CIS deletion with CRISPR/Cas9 enhances primary human NK cell
functions against allogeneic GBM cells
中澤務、前岡良輔、森本尭之、松田良介、中村光利、西村文彦、山田修一、中川一郎、中瀬裕之、辻村貴弘
第22回日本再生医療学会総会、2023年、京都
CRISPR/Cas9を用いたCIS欠損NK細胞の膠芽腫に対する抗腫瘍効果の検討
前岡良輔, 中澤務, 森本尭之, 松田良介, 西村文彦, 中川一郎,
辻村貴弘, 中瀬裕之
第40回日本脳腫瘍学会学術集会、2022年、千葉
膠芽腫スフェロイドモデルにおける遺伝子発現解析とNK細胞の傷害活性についての検討
森本尭之, 中澤務, 松田良介, 西村文彦, 中村光利, 山田修一,
中川一郎, 朴永銖, 辻村貴弘, 中瀬裕之
第40回日本脳腫瘍学会学術集会、2022年、千葉
CIS deletion by CRISPR/Cas9 enhances human NK cell-mediated
antitumor effects in glioblastoma
前岡良輔、中澤務、森本尭之、松田良介、西村文彦、中村光利、山田修一、中川一郎、辻村貴弘、中瀬裕之
第26回日本がん免疫学会総会、2022年、島根
Anti-tumor effect of genuine induced natural killer cells for
glioblastoma in vitro and vivo study
松田良介
、中澤務、森本尭之、前岡良輔、西村文彦、中川一郎、辻村貴弘、中瀬裕之
第26回日本がん免疫学会総会、2022年、島根
Natural killer
細胞を用いた膠芽腫に対する細胞移植治療の基礎的研究
松田良介 、中澤務、森本尭之、至田洋一、前岡良輔、
西村文彦、中川一郎、辻村貴弘、中瀬裕之
第22回日本分子脳神経外科学会、2022年、石川
CRISPR-Cas9によるTIM3ノックアウトNK細胞における膠芽腫細胞株への抗腫瘍効果の検討
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
第39回日本脳腫瘍学会学術集会 、2021年、兵庫
当科における膠芽腫に対するNK細胞療法の開発の歩み
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
日本脳神経外科学会第80回学術総会 、2021年、山梨
CRISPR-Cas9-Mediated TIM3 knockout in human Natural Killer Cells
Enhances Growth Inhibitory Effects on Human Glioma Cells.
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
第21回日本分子脳神経外科学会 、2021年、京都
The role of PD-1/PD-L1 pathway in anti-tumor effect of genuine
induced natural killer cells for glioblastoma in vitro and vivo
study
松田良介、中澤務、至田洋一、森本
尭之、西村文彦、中村光利、山田修一、中川一郎、辻村貴弘、中瀬裕之
第25回日本がん免疫学会総会、2021年、和歌山
CRISPR–Cas9–mediated TIM3 knockout in human Natural Killer Cells
Enhances Growth Inhibitory Effects on Human Glioma Cells
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
第25回日本がん免疫学会総会、2021年、和歌山
Efficient blockade of TIM3 by CRISPR-Cas9 in Human Natural
killer cells Enhances an antitumor effect in Human Glioblastoma
Cells
森本尭之、中澤務、松田良介、西村文彦、中村光利、山田修一、中川一郎、朴永銖、辻村貴弘、中瀬裕之
日本ゲノム編集学会第6回大会、2021年、福岡
当院におけるWT1ペプチド樹状細胞治療の経験
辻村貴弘、中村光利
第1回WT1樹状細胞研究会、2020年、Web会議
Establishment of highly purified human natural killer cells and
evaluation of their antitumor activity on glioblastoma
松田良介、中澤務、田中祥貴、至田洋一、中村光利、西村文彦、村上敏春、中川一郎、本山靖、辻村貴弘、中瀬裕之
第23回日本がん免疫学会総会、2019年、高知
膠芽腫に対する高純度NK細胞と免疫チェックポイント阻害薬併用による抗腫瘍効果の検討
至田洋一、中澤務、中村光利、辻村貴弘、森本尭之、田中祥貴、村上敏春、尾本幸治、松田良介、中川一郎、西村文彦、本山靖、朴永銖、中瀬裕之
第20回日本分子脳神経外科学会、2019年、東京
膠芽腫細胞に対する高純度NK細胞とTMZの併用による抗腫瘍効果とその機序の解析
至田洋一、中澤務、中村光利、辻村貴弘、田中祥貴、竹島靖浩、松田良介、田村健太郎、山田修一、中川一郎、西村文彦、横田浩、本山靖、朴永銖、中瀬裕之
第18回日本分子脳神経外科学会学術集会、2017年、山梨
高純度NK細胞を用いた膠芽腫細胞に対する抗腫瘍効果とTMZを用いた併用効果の基礎的検討
田中祥貴、中澤務、中村光利、辻村貴弘、尾本幸治、竹島靖浩、松田良介、田村健太郎、山田修一、中川一郎、西村文彦、横田浩、本山靖、朴永銖、中瀬裕之
第14回日本免疫治療学研究会学術集会、2017年、東京
ミノドロン酸の抗非小細胞肺癌効果の検討
安川元章、東条尚、川口剛史、河合紀和、中澤務、辻村貴弘
第56回日本肺癌学会学術集会、2015年、横浜
膠芽腫細胞株におけるミノドロン酸の抗腫瘍効果の検討
松田良介、中村光利、中澤務、西村文彦、辻村貴弘、中瀬裕之
第12回日本免疫治療学研究会学術集会、2015年、東京
ヒト末梢血由来細胞傷害性γδT細胞は膠芽腫細胞株を殺傷する
中澤務、中村光利、松田良介、朴永銖、本山靖、新靖史、弘中康雄、中川一郎、西村文彦、丸谷明子、王寺典子、辻村貴弘、王寺幸輝、吉川正英、中瀬裕之
第18回日本がん免疫学会総会、2014年、愛媛
ヒト神経膠芽腫細胞株に対するヒト末梢血由来γδT細胞の細胞傷害活性について
中澤務、中村光利、朴永銖、本山靖、弘中康雄、西村文彦、中川一郎、山田修一、松田良介、杉本正、竹島靖浩、丸谷明子、王寺幸輝、吉川正英、辻村貴弘、中瀬裕之
第13回日本分子脳神経外科学会学術集会、2012年、熊本
